Journal of Oral Health and Community Dentistry

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2007 | May-August | Volume 1 | Issue 2

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Nikita V Lolayekar, S Vidya Bhat

Disinfection Methods of Extracted Human Teeth

[Year:2007] [Month:May-August] [Volume:1] [Number:2] [Pages:3] [Pages No:27 - 29]

   DOI: 10.5005/johcd-1-2-27  |  Open Access |  How to cite  | 


Extracted human teeth are routinely used for educational purposes in dental institutions. In recent years infection control guidelines have been revised due to the possibility of cross-contamination from these extracted teeth. This study was done to determine the efficacy of some commonly used methods for disinfection/sterilization of extracted human teeth.



Urvashi Singla, Snehlata Kulhari

Genetics – Need to Evaluate its Role in Early Detection of Oral Squamous Cell Carcinoma (OSCC)

[Year:2007] [Month:May-August] [Volume:1] [Number:2] [Pages:3] [Pages No:30 - 32]

   DOI: 10.5005/johcd-1-2-30  |  Open Access |  How to cite  | 


The concept of cancer genetics is relatively new and considered more in prostate and breast cancer. Its role in OSCC has never been given much attention, which is the sixth most common malignancy worldwide. It is a tumour which can be treated by simple surgical procedure, if diagnosed at an early stage. Oral cavity and oropharynx are easily accessible for visualization. But high prevalence of oral abnormalities (5-15%) detected as a result of oral screening programmes (OSP) subjects large number of patients for biopsy which is impractical. Detection of early stage oral cancer is significantly impaired by absence of classic clinical characteristics of advanced oral cancer in early stage lesions. This influences 5 year survival rate for 80% of patients, despite major advances in surgery, chemotherapy, radiotherapy.

Many gene alterations have been implicated in development and progression of OSCC. Genetic differences is an important consideration to determine individual differences in susceptibility to chemical carcinogens. Many genetic changes are commonly observed in oral cancers. Salivary Transcriptome Diagnostics, based on specific mRNA signature in saliva as diagnostic marker, can be a suitable tool for development of non invasive diagnostic, chemoprevention, prognostic and follow up tests for cancer and also to detect cancer conversion of premalignant lesions. To summarize research on genetics will open new directions for estimation of risk of human cancer and its early diagnosis.



Vimoj Nair, Vivek Kaushal

Management of Radiation Induced Xerostomia in Head and Neck Cancers

[Year:2007] [Month:May-August] [Volume:1] [Number:2] [Pages:7] [Pages No:33 - 39]

   DOI: 10.5005/johcd-1-2-33  |  Open Access |  How to cite  | 


Head and neck squamous cell carcinoma is the most diverse class of malignancies lumped together under one diagnostic heading, occurring in several different sites and linked only by a common squamous histology. For cure in head and neck cancer dose of radiotherapy more than 60Gy are needed though the tolerance of normal organs e.g. salivary glands varies between 32Gy to 46Gy. Xerostomia is a major complication in patients who are receiving curative radiotherapy for head and neck cancer. Xerostomia is the main clinical effect that interferes with nutrition & use of dentures, deteriorates oral hygiene and predisposes patients to oral candidiasis and dental problems (e.g. dental caries). In the worst case, dry mouth can lead to osteoradionecrosis of the mandible. Treatment of radiation induced xerostomia calls for good hydration, optimal oral hygiene and prophylaxis of candidiasis. Therapeutic options are artificial saliva substitutes, mouth wetting agents and drugs like pilocarpine and amifostine. Modern radiotherapeutic techniques requiring meticulous planning may lead to prevention of radiation induced xerostomia, however once xerostomia establishes the satisfactory measures of control are limited.



Mahesh Goel

Geminated Maxillary Lateral Incisor with Talon's Cusp – A Rare Case Report

[Year:2007] [Month:May-August] [Volume:1] [Number:2] [Pages:3] [Pages No:40 - 42]

   DOI: 10.5005/johcd-1-2-40  |  Open Access |  How to cite  | 


A rare case of Geminated maxillary lateral incisor with Talon's cusp is reported. In order to relieve the crowding, align the anteriors and to facilitate the eruption of canine it was planned to extract the geminated tooth. The canine after complete eruption was recontoured to the shape of lateral incisor followed by the alignment of anterior teeth.



CM Marya, Rajesh Anegundi

Xeroderma Pigmentosa; Review and Case Report

[Year:2007] [Month:May-August] [Volume:1] [Number:2] [Pages:3] [Pages No:43 - 45]

   DOI: 10.5005/johcd-1-2-43  |  Open Access |  How to cite  | 


Xeroderma Pigmentosa is caused by an autosomal recessive allele. It is characterized by dry, pigmented skin, spidery blood vessels in the skin, skin cancers, and sometimes other abnormalities of both the eyes and brain. A harsh reaction to sunlight, such as severe sunburn and blistering at only a slight exposure, is a notable symptom and should be distinguished within the first year or two of life. The majority of the people who are born with these disorders die by early adulthood due to malignant cancers. This article reports a case of 6-year-old child suffering from XP with dental implications.


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