Journal of Oral Health and Community Dentistry

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VOLUME 14 , ISSUE 1 ( January-April, 2020 ) > List of Articles

Original Article

Determining the Efficacy of Three Potential Remineralizing Agents on Artificial Carious Lesions

Valluri Pratyusha Sai, Kakarla Pranitha, Avula Jogendra Sai Sankar, Muktineni Sridhar, Kundeti Siva Sankar, Adavikolanu Kesav Ramgopal

Keywords : Casein phosphopeptide–amorphous calcium phosphate, Remineralization, Remineralizing agents, Silver diamine fluoride, Theobromine

Citation Information : Sai VP, Pranitha K, Sankar AJ, Sridhar M, Sankar KS, Ramgopal AK. Determining the Efficacy of Three Potential Remineralizing Agents on Artificial Carious Lesions. J Oral Health Comm Dent 2020; 14 (1):1-5.

DOI: 10.5005/jp-journals-10062-0063

License: CC BY-NC 4.0

Published Online: 05-09-2020

Copyright Statement:  Copyright © 2020; The Author(s).


Abstract

Background: Present day, the focus has changed toward increasing the tooth resistance by topical application of remineralizing agents, which has resulted in the remarkable decline in dental caries. However, the remineralizing capacity of these agents remains questionable. Aim: To determine the efficacy of three commercially available remineralizing agents on artificially created carious lesions on primary teeth. Materials and methods: A total of 30 sound human primary anterior teeth were selected, decoronated, and randomly divided into three groups of 10 each: group I (FAgamin), group II (Theodent Classic), group III (GC Tooth Mousse). Baseline surface microhardness for each specimen was measured using a Digital Micro Vicker's hardness tester. Later these specimens were demineralized for 96 hours to assess intermediate surface microhardness values. Further, they were subjected to remineralization with their respective remineralizing agents for 14 days with a pH cycling model and final surface microhardness scores were assessed to determine the extent of remineralization. Results: The statistical analysis was done using ANOVA and Bonferroni multiple comparison tests, which showed that all the three remineralizing agents exhibited certain amount of remineralization. Group I showed the highest potential compared with the other groups, which was statistically significant (p < 0.05). Conclusion: All the three groups demonstrated remineralization of carious lesions by virtue of an increase in surface microhardness. Among the tested agents, 38% silver diamine fluoride (SDF) exhibited a superior remineralizing potential.


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