Journal of Oral Health and Community Dentistry

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VOLUME 4 , ISSUE Spl ( 2010 ) > List of Articles

RESEARCH ARTICLE

Future of Periodontal Regeneration

Ranjan Malhotra, Anoop Kapoor, Vishakha Grover, Nitin Verma, Jasjit Kaur Sahota

Citation Information : Malhotra R, Kapoor A, Grover V, Verma N, Sahota JK. Future of Periodontal Regeneration. J Oral Health Comm Dent 2010; 4 (Spl):38-47.

DOI: 10.5005/johcd-4-Spl-38

License: CC BY-NC 3.0

Published Online: 01-01-2014

Copyright Statement:  Copyright © 2010; The Author(s).


Abstract

The management of periodontal defects has been an ongoing challenge in clinical periodontics. In the recent past, attention has been focused more on regenerative and reconstructive therapies i.e. bone grafts, guided tissue regeneration, root conditioning, polypeptide growth factors, rather than on respective therapies. These therapeutic measures are shown to be limited in the predictability of healing and regenerative response in the modern clinical practice because oral environment presents several complicating factors that border regeneration. The 21st century appears to represent a time in history when there is a convergence between clinical dentistry and medicine, human genetics, developmental and molecular biology, biotechnology, bioengineering, and bioinformatics, resulting in the emergence of novel regenerative therapeutic approaches viz. tissue engineering, gene therapy and RNA interference. The focus of this review paper is to furnish and update the current knowledge of periodontal tissue engineering, gene therapy and RNA interference i.e. the future of periodontal regeneration.


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