Citation Information :
Taneja S, Chadha R, Dixit S, Nayar R. An In Vitro Comparison of Quantitative Dissolution of Human Pulp in Different Irrigating Solutions. J Oral Health Comm Dent 2010; 4 (2):28-33.
Pulp tissue from freshly extracted, intact vital premolars was removed in toto and was cut to get an approximate weight of 8.2 mg for each sample. Eighty samples thus obtained were divided into 4 groups of 20 samples each according to the irrigating solution used (5.25% NaOCl, 17% EDTA, BioPure MTAD and Distilled water (control group). Pulp tissue of specified equal weight (8.2 mg) was placed into each test tube of all groups carrying irrigants of measured volume (5ml each) at 37°C according to their specified subgroups time interval i.e. 10 min, 15 min, 20 min and 30 min respectively. The solution from each sample test tube was filtered and was left for overnight drying. The residual weight was calculated by filtration method. Results showed that the maximum amount of pulp was dissolved by 5.25% NaOCl at all time intervals. MTAD and 17% EDTA showed almost similar dissolution at all the time intervals.
The capabilities of sodium hypochlorite to digest organic debris from root canals with emphasis on accessory canals, thesis. Boston University 1970.
Chelation in Root canal therapy. Sartryk Odontol 1957;65:1–11.
Interactions of ethylenediamine tetraacetic acid with sodium hypochlorite in aqueous solutions. Int Endod J 2003;36:411–415.
Irrigation solution and methods for use. United States patent application 2003;0235804.
Evaluation of cytotoxicity of MTAD using the MTT- Tetrazolium method. J Endod 2003;29(10):654–657.
Tetracycline and its derivatives strongly bind to and are released from the tooth surface in active form. J Periodontol 1983;54:580–585.
Quantitative study of sodium hypochlorite as an in vitro endodontic irrigant. J Endod 1977;3(5):194–196.
Dissolution of bovine pulp tissue by endodontic solutions. Scand J Dent Res 1980;88(5):406–411.
Sulfuric acid for opening root canals. Dental Cosmos 1894;36:957–959.
Solution of pulp tissue by chemical agents. J Am Dent Assoc 1941;28:223–225.
Use of a bottle warmer to increase 4% sodium hypochlorite tissue dissolution ability on bovine pulp. Aus Endod J 2008;34(1):39–42.
Dissolution of bovine pulp tissue by endodontic solutions. Scand J Dent Res 1980;88(5):406–411.
Quantitative analysis of the solubilizing action of MTAD, Sodium Hypochlorite, and EDTA on bovine pulp and dentin. J Endod 2003;29(5):334–337.
Dissolution of pulp tissue by aqueous solution of chlorhexidine digluconate and chlorhexidine digluconate gel. Int Endod J 2004;37:38–41.
The solvent action of sodium hypochlorite on bovine tendon collagen, bovine pulp, and bovine gingiva. Oral Surg Oral Med Oral Pathol 1985;60(3):322–326.
The shelf-life of sodium hypochlorite irrigating solutions. Aust Dent J 2001;46(4):269–276.
Factors promoting the tissue dissolving capability of sodium hypochlorite. Int Endod J 1982;15(4):187–196.
Solvent effect of various dilutions of sodium hypochlorite on vital and necrotic tissue. J Endod 1981;7(10):466–469.
