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VOLUME 16 , ISSUE 3 ( September-December, 2022 ) > List of Articles


Effects of Chewing Gums Containing Xylitol and Sorbitol on Salivary Microflora, Plaque, and Gingiva: A Systematic Review

S Maya Sri, P Nimmy

Keywords : Chewing gum, Gingiva, Plaque, Salivary microflora, Sorbitol, Xylitol

Citation Information : Sri SM, Nimmy P. Effects of Chewing Gums Containing Xylitol and Sorbitol on Salivary Microflora, Plaque, and Gingiva: A Systematic Review. J Oral Health Comm Dent 2022; 16 (3):138-141.

DOI: 10.5005/jp-journals-10062-0155

License: CC BY-NC 4.0

Published Online: 23-03-2023

Copyright Statement:  Copyright © 2022; The Author(s).


Aim: This study is targeted to assess the effect of chewing gums containing xylitol and sorbitol on salivary microflora, plaque, and gingiva. Materials and methods: The literature review was performed using PubMed, Cochrane Central Register of Controlled Trials (CENTRAL), Science Direct, Lilacs, Google Scholar, Gray Literature, and Ovid MEDLINE using MeSH Terms—Chewing gums, xylitol, and sorbitol. Among the total of 870 titles appearing from various sources, 746 records were screened, and 70 were related to the research. This review is described according to PRISMA guidelines for systematic review. Results: Four randomized control trial articles were included, effects of xylitol and sorbitol chewing gums were compared. Among the four trials, three found statistically significant differences favoring the effects of chewing gums containing xylitol and sorbitol. Conclusion: Thereby, we can conclude that xylitol- and sorbitol-containing chewing gums affect salivary microflora, plaque, and gingiva. Clinical significance: Prevention of plaque and salivary microflora using xylitol and sorbitol.

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