Journal of Oral Health and Community Dentistry

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VOLUME 16 , ISSUE 2 ( May-August, 2022 ) > List of Articles


Orthokeratinized Odontogenic Cyst in Posterior Maxilla: A Rare Diagnosis

Niyati Mishra, Sumit Bhatt, Himanshu Pratap Singh

Keywords : Maxillary, Odontogenic keratocyst

Citation Information : Mishra N, Bhatt S, Singh HP. Orthokeratinized Odontogenic Cyst in Posterior Maxilla: A Rare Diagnosis. J Oral Health Comm Dent 2022; 16 (2):106-109.

DOI: 10.5005/jp-journals-10062-0066A

License: CC BY-NC 4.0

Published Online: 13-09-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Aim: Aim of this case report is to discuss and identify a rare diagnosis yet seen commonly in oral and maxillofacial field and often misdiagnosed as odontogenic keratocyst (OKC). Background: The term “odontogenic keratocyst” was first described by Philipsen in 1956. This was then modified by World Health Organization (WHO) in 2005 as “odontogenic unicystic” or “multicystic intraosseous tumor” with a distinctive parakeratinized stratified squamous epithelial lining and the propensity for aggressive and infiltrative activity. It has a male predilection and bimodal age distribution. Orthokeratinized OKC makes up to 2.1% of all the cystic lesions of the jaws. Case description: A young female patient aged 18 years reported to our department with the chief complaint of pus like discharge from upper left back tooth region for the past 2 months. After all the clinical, radiological, and histopathological findings, the patient was then diagnosed with orthokeratinized odontogenic cyst (OOC) of posterior maxilla. Conclusion: Orthokeratinized odontogenic cyst has clinical, histological, and biological characteristics that distinguish it from OKC, including better prognosis and decreased recurrence rate. Clinical significance: It is important to distinguish between OKC and OOC as the latter shows less chances of recurrence and less scope for malignancy transformation.

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  1. Dong Q, Pan S, Sun LS, et al. Orthokeratinized odontogenic cyst: A clinicopathologic study of 61 cases. Arch Pathol Lab Med 2010;134(2):271–275. DOI: 10.5858/134.2.271.
  2. Iwai H, Suzuki T, Suzuki T, et al. Histopathological examination and literature review of orthokeratinized odontogenic cyst. Open J Stomatol 2019;9(05):125–135.
  3. González Galván MDC, García–García A, Anitua–Aldecoa E, et al. Orthokeratinized odontogenic cyst: A report of three clinical cases. Case Rep Dent 2013. 2013:672383. DOI: 10.1155/2013/672383.
  4. Mahdavi N, Taghavi N. Orthokeratinized odontogenic cyst of the maxilla: Report of a case and review of the literature. Turk Patoloji Derg 2017;33:81–85. DOI: 10.5146/tjpath.2014.01273.
  5. Mahdavi N, Zavarei M, Derakhshan S, et al. Orthokeratinized odontogenic cyst: Report of eight cases and review of literature regarding its malignant transformation. J Oral Maxillofac Pathol 2021;25(Suppl. 1):S11–S17. DOI: 10.4103/jomfp.JOMFP_1_20.
  6. Macdonald-Jankowski DS. Orthokeratinized odontogenic cyst: a systematic review. Dentomaxillofacial Radiology 2010;39(8): 455–467. DOI: 10.1259/dmfr/19728573.
  7. Dong Q, Pan S, Sun LS, et al. Orthokeratinized odontogenic cyst: a clinicopathologic study of 61 cases. Archives of pathology & laboratory medicine 2010;134(2):271–275. DOI: 10.5858/134.2.271.
  8. Sameerudeen MS, Mugundan RN, Shwetha S, et al. Expect the unexpected: A rare case of orthokeratinized odontogenic cyst and its surgical management. Hellenic Arch Oral Maxillofac Surg 2021;2:119–124. DOI: 10.54936/haoms222119124.
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