Herbal Mouthwash for the Management of Oral Diseases: A Review on the Current Literature
Vrushali R Khobragade, Prashanthkumar Vishwakarma, Arun S Dodamani, Minal M Kshirsagar, Sulakshana N Raut, Rahul N Deokar
Citation Information :
Khobragade VR, Vishwakarma P, Dodamani AS, Kshirsagar MM, Raut SN, Deokar RN. Herbal Mouthwash for the Management of Oral Diseases: A Review on the Current Literature. J Oral Health Comm Dent 2021; 15 (2):70-77.
Several different varieties of mouthwashes are accessible to us nowadays, including chemical as well as herbal formulations. Appropriate mouthwash can be selected depending on the oral condition, risk, and efficiency of mouthwash. As mentioned in the literature also Mother Nature has provided us abundant medicinal herbs with antibacterial and antimicrobial properties. Though we are having very scarce data on the medicinal properties of these herbal plants, they are still in use in treating various periodontal diseases and other oral diseases. Knowing scientific expression of the actual effects of the herbal medicine is at most important for the beneficiaries. In the course of this bibliographical revision, papers were collected to validate the ancestral uses of herbs and conclude that the use of plants to treat oral conditions should be based on the experimental studies, verifying their suitability for dental treatments. Oral healthcare professionals would find this review helpful for accurate mouthwash selection while dealing with different conditions of the oral cavity.
Page RC, Kornman KS. The pathogenesis of human periodontitis: an introduction. Periodontol 2000 1997;14(1):9–11. DOI: 10.1111/j.1600-0757.1997.tb00189.x.
DePaola LG, Overholser CD, Meiller TF, et al. Chemotherapeutic inhibition of supragingival dental plaque and gingivitis development. J Clin Periodontol 1989;16(5):311–315. DOI: 10.1111/j.1600-051x.1989.tb01661.x.
Dona BL, Gründemann LJ, Steinfort J, et al. The inhibitory effect of combining chlorhexidine and hydrogen peroxide on 3rd day plaque accumulation. J Clin Periodontol 1998;25(11 Pt 1):879–883. DOI: 10.1111/j.1600-051x.1998.tb02385.x.
Siddeshappa ST, Bhatnagar S, Yeltiwar RK, et al. Comparative evaluation of antiplaque and antigingivitis effects of an herbal and chlorine dioxide mouthwashes: a clinicomicrobiological study. Indian J Dent Res 2018;29(1):34. DOI: 10.4103/ijdr.IJDR_391_16.
Albert-Kiszely A, Pjetursson BE, Salvi GE, et al. Comparison of the effects of cetylpyridinium chloride with an essential oil mouth rinse on dental plaque and gingivitis—a six month randomized controlled clinical trial. J Clin Periodontol 2007;34(8):658–667. DOI: 10.1111/j.1600-051X.2007.01103.x.
Najafi MH, Taheri M, Mokhtari MR, et al. Comparative study of 0.2% and 0.12% digluconate chlorhexidine mouth rinses on the level of dental staining and gingival indices. Dent Res J (Isfahan) 2012;9(3):305. drj.mui.ac.ir/index.php/drj/article/view/1089
Kaur H, Jain S, Kaur A. Comparative evaluation of the antiplaque effectiveness of green tea catechin mouthwash with chlorhexidine gluconate. J Indian Soc Periodontol 2014;18(2):178–182. DOI: 10.4103/0972-124X.131320.
Pizzo G, Guiglia R, Imburgia M, et al. The effects of antimicrobial sprays and mouthrinses on supragingival plaque regrowth: a comparative study. J Periodontol 2006;77(2):248–256. DOI: 10.1902/jop.2006.050116.
Gupta D, Nayan S, Tippanawar HK, et al. Are herbal mouthwash efficacious over chlorhexidine on the dental plaque? Pharmacognosy Res 2015;7(3):277–281. DOI: 10.4103/0974-8490.155874.
Bhat N, Mitra R, Reddy JJ, et al. Evaluation of efficacy of chlorhexidine and a herbal mouthwash on dental plaque: an in vitro comparative study. Int J Pharm Bio Sci 2013;4(3):625–632. Available from: https://www.researchgate.net/publication/269404420
Mahajan R, Khinda P, Gill A, et al. Comparison of efficacy of 0.2% chlorhexidine gluconate and herbal mouthrinses on dental plaque: an in vitro comparative study. Eur J Med Plants 2016;13(2):1–11. DOI: 10.9734/EJMP/2016/23318.
Mali AM, Behal R, Gilda SS. Comparative evaluation of 0.1% turmeric mouthwash with 0.2% chlorhexidine gluconate in prevention of plaque and gingivitis: a clinical and microbiological study. J Indian Soc Periodontol 2012;16(3):386–391. DOI: 10.4103/0972-124X.100917.
Manipal S, Hussain S, Wadgave U, et al. The mouthwash war-chlorhexidine vs. herbal mouth rinses: a meta-analysis. J Clin Diagn Res 2016;10(5):81. DOI: 10.7860/JCDR/2016/16578.7815.
Naiktari RS, Gaonkar P, Gurav AN, et al. A randomized clinical trial to evaluate and compare the efficacy of triphala mouthwash with 0.2% chlorhexidine in hospitalized patients with periodontal diseases. J Periodontal Implant Sci 2014;44(3):134–140. DOI: 10.5051/jpis.2014.44.3.134.
Kothiwale SV, Patwardhan V, Gandhi M, et al. A comparative study of antiplaque and antigingivitis effects of herbal mouthrinse containing tea tree oil, clove, and basil with commercially available essential oil mouthrinse. J Indian Soc Periodontol 2014;18(3):316. DOI: 10.4103/0972-124X.134568.
Prasad KR, John S, Deepika V, et al. Anti-plaque efficacy of herbal and 0.2% chlorhexidine gluconate mouthwash: a comparative study. J Int Oral Health 2015;7(8):98. “https://dx.doi.org/10.5812/ijo.96472''10.5812/ijo.96472
Padiyar B, Marwah N, Gupta S, et al. Comparative evaluation of effects of triphala, garlic extracts, and chlorhexidine mouthwashes on salivary Streptococcus mutans counts and oral hygiene status. Int J Clin Pediatr Dent 2018;11(4):299. DOI: 10.5005/jp-journals-10005-1530.
Umar D, Dilshad B, Farhan M, et al. The effect of pomegranate mouthrinse on Streptococcus mutans count and salivary pH: an in vivo study. J Adv Pharm Technol Res 2016;7(1):13. DOI: 10.4103/2231-4040.173266.
Mali GV, Dodamani AS, Karibasappa GN, et al. Comparative evaluation of Arimedadi oil with 0.2% chlorhexidine gluconate in prevention of plaque and gingivitis: a randomized clinical trial. J Clin Diagn Res 2016;10(7):31. DOI: 10.7860/JCDR/2016/19120.8132.
Abdulbaqi HR, Himratul-Aznita WH, Baharuddin NA. Evaluation of Salvadora persica L. and green tea anti-plaque effect: a randomized controlled crossover clinical trial. BMC Complement Altern Med 2016;16(1):493. DOI: 10.1186/s12906-016-1487-0.
Sedigh-Rahimabadi M, Fani M, Rostami-chijan M, et al. A traditional mouthwash (Punica granatum var pleniflora) for controlling gingivitis of diabetic patients: a double-blinded randomized controlled clinical trial. J Evid Based Complementary Altern Med 2017;22(1):59–67. DOI: 10.1177/2156587216633370.
Mishra R, Tandon S, Rathore M, et al. Antimicrobial efficacy of probiotic and herbal oral rinses against Candida albicans in children: a randomized clinical trial. Int J Clin Pediatr Dent 2016;9(1):25. DOI: 10.5005/jp-journals-10005-1328.
He JY, Qi GG, Huang WJ, et al. Short-term microbiological effects of scaling and root planing and essential-oils mouthwash in Chinese adults. J Zhejiang Univ Sci B 2013;14(5):416–425. DOI: 10.1631/jzus.B1200350.
Rezaei S, Rezaei K, Mahboubi M, et al. Comparison the efficacy of herbal mouthwash with chlorhexidine on gingival index of intubated patients in Intensive Care Unit. J Indian Soc Periodontol 2016;20(4):404. DOI: 10.4103/0972-124X.194269.
Ardakani MT, Ghassemi S, Mehdizadeh M, et al. Evaluating the effect of Matricaria recutita and Mentha piperita herbal mouthwash on management of oral mucositis in patients undergoing hematopoietic stem cell transplantation: A randomized, double blind, placebo controlled clinical trial. Complement Ther Med 2016;29:29–34. DOI: 10.1016/j.ctim.2016.08.001.
Parwani SR, Parwani RN, Chitnis PJ, et al. Comparative evaluation of anti-plaque efficacy of herbal and 0.2% chlorhexidine gluconate mouthwash in a 4-day plaque re-growth study. J Indian Soc Periodontol 2013;17(1):72. DOI: 10.4103/0972-124X.107478.
Priya BM, Anitha V, Shanmugam M, et al. Efficacy of chlorhexidine and green tea mouthwashes in the management of dental plaque-induced gingivitis: a comparative clinical study. Contemp Clin Dent 2015;6(4):505. DOI: 10.4103/0976-237X.169845.
Aghili H, Nadoushan AA, Herandi V. Antimicrobial effect of zataria multiflora extract in comparison with chlorhexidine mouthwash on experimentally contaminated orthodontic elastomeric ligatures. J Dent (Tehran) 2015;12(1):1. https://pubmed.ncbi.nlm.nih.gov/26005448
Varghese A, Babu HM, Kukkera PN. Comparative evaluation of efficacy of Murraya koenigii and chlorhexidine gluconate in the treatment of gingivitis: a randomized controlled clinical trial. J Indian Soc Periodontol 2018;22(5):427. DOI: 10.4103/jisp.jisp_112_18.
Balappanavar AY, Sardana V, Singh M. Comparison of the effectiveness of 0.5% tea, 2% neem and 0.2% chlorhexidine mouthwashes on oral health: a randomized control trial. Indian J Dent Res 2013;24(1):26. DOI: 10.4103/0970-9290.114933.
Chatterjee A, Debnath K, Rao NK. A comparative evaluation of the efficacy of curcumin and chlorhexidine mouthrinses on clinical inflammatory parameters of gingivitis: a double-blinded randomized controlled clinical study. J Indian Soc Periodontol 2017;21(2):132. DOI: 10.4103/jisp.jisp_136_17.
Yadav M, Kaushik M, Roshni R, et al. Effect of green coffee bean extract on Streptococcus mutans count: a randomised control trial. J Clin Diagn Res 2017;11(5):68. DOI: 10.7860/JCDR/2017/25743.9898.
Cullinan MP, Powell RN, Faddy MJ, et al. Efficacy of a dentifrice and oral rinse containing sanguinaria extract in conjunction with initial periodontal therapy. Aust Dent J 1997;42(1):47–51. DOI: 10.1111/j.1834-7819.1997.tb00096.x.
Braga FT, Santos AC, Bueno PC, et al. Use of Chamomilla recutita in the prevention and treatment of oral mucositis in patients undergoing hematopoietic stem cell transplantation: a randomized, controlled, phase II clinical trial. Cancer Nurs 2015;38(4):322–329. DOI: 10.1097/NCC.0000000000000194.
Akca AE, Akca G, Topçu FT, et al. The comparative evaluation of the antimicrobial effect of propolis with chlorhexidine against oral pathogens: an in vitro study. Biomed Res Int 2016;2016:3627463. DOI: 10.1155/2016/3627463.
Vangipuram S, Jha A, Bhashyam M. Comparative efficacy of aloe vera mouthwash and chlorhexidine on periodontal health: a randomized controlled trial. J Clin Exp Dent 2016;8(4):442. DOI: 10.4317/jced.53033.
Beheshti-Rouy M, Azarsina M, Rezaie-Soufi L, et al. The antibacterial effect of sage extract (Salvia officinalis) mouthwash against Streptococcus mutans in dental plaque: a randomized clinical trial. Iran J Microbiol 2015;7(3):173. https://pubmed.ncbi.nlm.nih.gov/26668706
Gupta D, Jain A. Effect of cinnamon extract and chlorhexidine gluconate (0.2%) on the clinical level of dental plaque and gingival health: a 4-week, triple-blind randomized controlled trial. J Int Acad Periodontol 2015;17(3):91–98. https://pubmed.ncbi.nlm.nih.gov/26373226
Freires ID, Alves LA, Ferreira GL, et al. A randomized clinical trial of Schinus terebinthifolius mouthwash to treat biofilm-induced gingivitis. J Evid Based Complement Alternat Med 2013;2013:873907. DOI: 10.1155/2013/873907.